Introduction to Biology II at Amherst College
2010


DATE |
SUBJECT |
READING |
LAB |
||||
Drosophila |
Yeast |
Other |
|||||
9/8 Wed |
Introductions; Bonds and Water |
Chps. 1 & 2 |
NO LAB |
||||
9/10 |
Cells and Membrane Structure |
69-72, 96-101, 105-107 |
|||||
9/13 |
Membrane Transport |
108-112 |
|
Yeast Extraction Cultures |
Membrane Permeability |
||
9/14 4th H |
Pre-Lab: Overview (required) |
|
|||||
9/15 |
Protein Structure |
38-48 |
|||||
9/17 |
Enzymes and Cellular Reactions |
118-131 |
|||||
9/20 |
Enzymatic Mechanisms & Regulation |
131-135 |
|
Yeast Extraction
|
Protein Structure |
||
9/21 4th H |
Weekly lecture review |
|
|||||
9/22 |
Bioenergetics I: Metabolism |
138-144 |
|||||
9/24 |
Bioenergetics I: Glycolysis & Fermentation |
147-148 |
|||||
9/27 |
Proteins and Inborn Errors of Metabolism |
375-376 |
|
Yeast |
Protein Structure |
||
9/28 4th H |
Weekly lecture review |
|
|||||
9/29 |
One Gene-One Enzyme |
256-260 |
|||||
10/1 |
Inheritance & Mendel’s 2 Laws |
206-216 |
|||||
10/4 |
Pedigrees, incomplete and co dominance |
216-219 |
Drosophila I |
|
Enzyme |
||
10/5 4th H |
Exam review session |
|
|||||
10/5 Tues 7:30 pm Exam I (covers 9/8 – 9/29) |
|||||||
10/6 |
Multiple Alleles, Multiple Genes and Complex Phenotypes |
219-223 |
|||||
10/8 |
Chromosomes, Meiosis |
193-202 |
|||||
10/11 |
FALL BREAK |
NO LAB |
|||||
10/13 |
Gene Mapping |
223-225 |
|||||
10/15 |
Sex Chromosomes, Sex linkage |
225-229 |
|||||
10/18 |
DNA: Discovery and Structure |
233-241 |
Drosophila I |
|
Mitosis, Meiosis & Recombination |
||
10/19 4th |
Mapping exercises, mi.&me. rev |
|
|||||
10/20 |
DNA Replication |
241-249 |
|||||
10/22 |
PCR, DNA Sequencing |
249-253 |
|||||
10/25 |
Central Dogma, Transcription, Gene Structure |
256-264,313 |
|
Yeast |
|
||
10/26 4th |
Exam Review Session |
|
|||||
10/26 Tues 7:30 pm Exam II (covers 10/1 – 10/22) |
|||||||
10/27 |
RNA Processing, Splicing, Genome Structure |
313-318, 324-325, 306-311 |
|||||
10/29 |
Translation & the Genetic Code |
264-272 |
|||||
11/1 |
Mutations |
274-279 |
Drosophila I (F2) |
Yeast |
|
|
11/2 4th H |
Mutations exercises |
|
||||
11/3 |
Gene Regulation, Prokaryotic |
296-300 |
||||
11/5 |
Gene Regulation, Eukaryotic |
318-324,326-7 |
||||
11/8 |
RNA Interference, microRNAs |
325,365 |
Gene annotation I |
Identify Yeast Mutants |
PCR of |
|
11/9 4th H |
Gene regulation exercises |
|
||||
11/10 |
Genomic Variation |
311-3, 355-6, 393-396, 300-2 |
||||
11/12 |
Recombinant DNA |
293-5, 352-355, 358-364 |
||||
11/15 |
Biotechnology |
365-369 |
Gene annotation II |
|
Gel Electro-phoresis |
|
11/16 4th |
Exam Review Session |
|
||||
11/17 |
Bioenergetics II: Mitochondria |
76, 82-3, 148- 150 |
||||
11/17 Wed 7:30 pm Exam III (covers 10/25 – 11/15) |
||||||
11/19 |
Bioenergetics II: Mitochondria |
150-154 |
||||
11/22-26 |
THANKSGIVING BREAK |
|||||
11/29 |
Bioenergetics II: Photosynthesis |
83-6, 160-168 |
Gene annotation III |
Yeast Complementation |
|
|
11/30 4th |
Weekly lecture review |
|
||||
12/1 |
Bioenergetics II: Photosynthesis |
169-172 |
||||
12/3 |
Protein Trafficking and Cytoskeleton-Based Movement |
86-90; 75-82; 113-114 |
||||
12/6 |
Mitosis and Cell Division |
180-183, 187-192 |
Gene annotation IV |
Score Complementation
|
|
|
12/7 4th H |
Weekly lecture review |
|
||||
12/8 |
Cell Cycle Control, Signaling and Cancer |
184-187; 386-90; 332-345 |
||||
12/10 |
Developmental Biology I: Fertilization, Stem Cells, Cloning |
427-35 |
||||
12/13 |
Developmental Biology II: Differentiation |
435-39; 441-445 |
NO LAB |
|||
12/14 4th |
Weekly lecture review |
|
||||
12/15 |
Discussion: Case studies in gene therapy |
375-378,391-393 |
||||
TBA |
Exam Review Session |
|||||
Course structure;
Three lectures a week - lecture notes will be posted on the course Blackboard site following each lecture
One 4th-hour session a week (Tuesday 1:00-1:50 PM) - These sessions will generally provide time with a faculty member to clarify topics raised in lecture and/or an opportunity to do in-class exercises. Students are encouraged to bring questions. Note that two required lab introductions will also be given during 4th hours.
Personal Response System (PRS) transmitters (‘clickers’) - Student responses recorded via PRS transmitters to questions posed in lecture or fourth hour sessions will enable professors to instantly assess student understanding of key concepts.
One study group meeting a week - These sessions will be staffed by the lecture teaching assistants and will focus on answering questions about the problem sets. Sign up for a particular session will occur during the first week of class. Problem sets will be collected by the lecture TA’s during the weekly study groups and graded for extent of completion (see below).
Problem Sets – Problem sets will be handed out throughout the semester as an additional way for students to test their understanding of lecture material. Problem set questions will generally be similar in style to exam questions. Questions about the problem sets will be answered in the weekly study groups. The problem sets will then be collected the following week and graded on a 0-1-2 scale (0=problem set not handed in; 1=problem set handed in, but is not complete and/or shows lack of effort; 2=problem set complete and shows good effort). We anticipate that completing the problem sets will have a beneficial effect on student learning and subsequent performance on the lecture exams.
One three-hour laboratory session a week - attendance is absolutely mandatory
Blackboard Site – Check for announcements and course documents.
Examinations:
There will be four examinations, each covering about 1/4 of the course. Three of these exams will occur on a weekday evening (see schedule) at 7:30 PM. The exams will be designed as 1 hour exams, but you will be given up to 2 hours if needed. The last of the exams will occur during finals period, but will otherwise be like the others, covering only the last 1/4 of the course. The exams will cover the following material:
Exam Date |
Material Covered |
Exam Location |
10/5, Tuesday |
9/8 - 9/29 |
Merrill 2 |
10/26, Tuesday |
10/1 - 10/22 |
Merrill 2 |
11/17, Wednesday |
10/25 - 11/15 |
Merrill 2 |
TBA (Finals period) |
11/17 - 12/15 |
TBA |
In case of scheduling conflicts, exams may be taken early, either on the day before (2-4 PM) or the same day (2:30-4:30 PM) of the exam. Failure to show up at an exam will earn a “0” for that exam. Postponements for medical reasons require a letter from your Dean. Please mark these dates in your calendars NOW!
Grading: The four lecture exams will together determine 65% of your final grade. Completion of problem sets will account for 3% of your grade and PRS participation will count for 2% of your grade. The remaining 30% will be determined by your attendance in laboratory and your performance on the various required laboratory reports that you turn in during the semester. The laboratory reports will not all carry the same weight - the comprehensive yeast report, for example, will count about three times as heavily as the Drosophila report. The due dates and approximate lengths for the lab reports are listed on the laboratory schedule. Note: lab reports not turned in by the due date will be subject to late penalties, with the penalty increasing each day that the report is late.
Office Hours:
Professor Dick Poccia 1:00 PM - 11:00 AM, Wed/Fri LSB 324 dlpoccia@amherst.edu 542-2143
Professor Amy Springer 11:00 – 11:59 AM, Wed/Thurs LSB 424 aspringer@amherst.edu 542-5341
Dr. Julie Emerson 10:30 – 11:30 AM, Wed/Fri LSB 322 jemerson@amherst.edu 542-8381
We encourage you to stop by any time during these hours; if you absolutely cannot make these times, please contact us by e-mail or telephone to set up an alternative appointment.
Lecture TAs: Alex Chang, Paul Cohen and Fabiana Kreines
Lecture TA Study Group Times:TBD
Every person's education is the product of his or her own intellectual effort and participation in a process of critical exchange. Amherst cannot educate those who are unwilling to submit their own work and ideas to critical assessment. Nor can it tolerate those who interfere with the participation of others in the critical process. Therefore, the College considers it a violation of the requirements of intellectual responsibility to submit work that is not one's own or otherwise to subvert the conditions under which academic work is performed by oneself or by others. For Bio 19: Any incidences of cheating will be reported to the Dean’s Office and will result in significant penalty, including the possibility of an “F” in the course.
Return to Poccia Home
Page.