Introduction to Biology II at Amherst College

2005

Biology 19

MOLECULES, GENES AND CELLS

Profs. Goutte/Poccia/Emerson

 

Schedule (Fall 2005)
Date Prof Topic Reading Lab
Sep. 7 CG Inheritance and Mendel's First Law 187-194 --
Sep. 9 CG Mendel II: Independent Assortment 194-197
Sep. 12 CG Gene/Allele Interactions 197-200
Sep. 14 CG Multiple Genes 200-202 Yeast Mutagenesis
Sep. 16 DP Genes and Proteins 340
Sep. 19 DP One Gene-One Enzyme 233-235
Sep. 21 DP Protein Structure 37-45 Droso. I ; Yeast Replica Plating
Sep. 23 DP Biochemical Reactions, Enzymes 106-119
Sep. 26 DP Enzyme Regulation 119-123
Sep. 28 DP Chromosomes 169-170 Identify Yeast Mutants; Enzymes I
Sep. 30 DP Mitosis/Meiosis 160-173;171-174;177-182
Oct. 3 DP Cell Cycle 155-159; 164-169
Oct. 5 CG Sex Chromosomes & Gene Linkage 202-209  
Oct. 7 CG Gene Mapping 202-205
Oct. 10 CG FALL BREAK  
Oct. 12 CG Genetic Transformation 213-217 Yeast Complementation; Droso. I (F1); Enzymes II
Oct. 14 CG DNA Structure 217-220
Oct. 17 CG DNA Replication 220-229
Oct. 19 CG Gene Expression, RNA 236-239 Droso. I (F2)
Oct. 21 CG Splicing 285-290
Oct. 24 CG Genetic Code 239-241
Oct. 26 CG Translation 223-230 Droso. II (Po); Score Compl.; Yeast Irrad.
Oct. 28 CG Mutation and Recombination  
Oct. 31 DP Membrane Structure 87-90
Nov. 2 DP Surface/ Junctions 82-84;90-94 Irrad. Replica Plating; Yeast Extraction; Mitosis
Nov. 4 DP Plasma Membrane Transport 94-100
Nov. 7 DP Glycolysis and Fermentation 125-131
Nov. 9 DP Glycolysis and Fermentation 137-139 Droso. II (F1); Membrane Transport;
Nov. 11 DP Mitochondria 60-61;68-79;131-136
Nov. 14 DP Mitochondria/Chloroplasts 139-143
Nov. 16 DP Chloroplasts 145-160 ; Droso. II (F2) Class Data; Score Irrad.
Nov. 18 DP Membrane Traffic/ER & Golgi 72-75;100-104
Nov. 20-27 DP THANKSGIVING  
Nov. 28 DP Cytoskeleton and Motility 79-82 --
Nov. 30 DP Signaling 279-293;301-315 Yeast Extraction
Dec. 2 CG Gene Regulation, General and Prokaryotic 269-274
Dec. 5 CG Gene Regulation, Eukaryotic 290-299; fig 14.8
Dec. 7 CG Recombinant DNA-Biotechnology 317-326;330-334  
Dec. 9 CG DNA Sequencing; Genomics 3279-284;230-231;335-337;358-361 Gel Electrophoresis and Chromatography
Dec. 12 CG Biotechnology DNA/RNA Hybridization; DNA Chips 327-328
Dec. 14 CG Molecular Medicine 339-350;355-357 --

Text is LIFE - THE SCIENCE OF BIOLOGY, 6th EDITION

Wm. K. Purves, David Sadava, Gordon H. Orians, H. Craig Heller, Life: The Science of Biology 7 th Edition, Sinauer Assoc. Inc.; W. H. Freeman & Co., 2001.

Examination and Grades:

There will be four examinations, each covering about 1/4 of the course. Three of these exams will occur during the 4th hour of the course (Thur 1:00-2:00 PM). The last of the exams will occur during Finals period, but will otherwise be like the others, covering only the last 1/4 of the course. The exams will cover the following material:

Exam Date Material Covered
October 5 Sep. 7- Sep. 26
October 26 Sep. 28 - Oct . 21
November 16 Oct. 24 - Nov. 11
Finals Period Nov. 14 - Dec. 14



These exams will together determine 70% of your final grade. The remaining 30% will be determined by your performance in laboratory and on the various laboratory reports required during the semester. The laboratory reports will not all carry the same weight - the comprehensive yeast report, for example, will count about three times as heavily as one of the Drosophila reports. The due dates for these will be:

Enzymes 10/18 - 10/21 in lab 2-3 pgs. plus figures
Dros. I 10/31 in class 2-3 pgs. class data available 10/24
Transport 11/18 in lab handout in lab
Dros. II 12/2 in class calc genetic map and answer questions posted on Course Info 11/19
Yeast 12/14 in JE box full report format due at 5 pm

Except for the scheduled examinations, attendance for the 4th hour (Thur 1:00-2:00 PM) will be optional, unless otherwise mentioned. These sessions will generally provide clarification of topics raised in lecture, or of practice problem sets and exams.

** The Drosophila lab scheduled for the week of Fall Break requires you to come into lab some time during the week to count F2 progeny. The procedure will be discussed during the lab period of the week prior (10/7).

Office Hours:

We will be happy to make appointments to meet with anyone who needs help, or if you prefer, stop by during office hours:

 

Lecture TAs:

Prof. Goutte Rm 427 LSB M 12-1

Prof. Poccia Rm 324 LSB M 1-2

Prof. Emerson Rm 322 LSB T,F 10-11

For some interesting web sites, click below:

Kimball's Biology Pages

http://www.ultranet.com/~jkimball/BiologyPages

More about Mendel

http://www.netspace.org/MendelWeb/

Set up some virtual Drosophila crosses

http://vflylab.calstatela.edu/edesktop/VirtApps/VflyLab/IntroVflyLab.html

Online Mendelian Inheritance in Man

http://www.ncbi.nlm.nih.gov/Omim/

Human chromosome maps

http://www.ncbi.nlm.nih.gov/Omim/

ftp://ncbi.nlm.nih.gov/repository/OMIM/genemap

National Center for Biotechnology Information (NIH)

http://www.ncbi.nlm.nih.gov/

MIT's biology hypertext page

http://esg-www.mit.edu:8001/bio/7001main.htm

The big (beautiful) picture book of viruses

http://www.tulane.edu/~dmsander/Big_Virology/BVHomePage.html




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